Biological age is the fundamental concept of the present study ch11, ch12, ch57 ch66. Aging is viewed as an ongoing accumulation of resources for sustaining life. Biological age is related with health which also depends on resources accumulated by the organism. Yet health is more than just biological age. Health depends also on how fast these resources are mobilized following injury.
We start with three CA with the same age structure. CA-1 and CA-2 exchange resources (biological age). When CA-1 age is lower than CA-2, the latter feeds it with the missing resources (biological age) and vice versa. In addition, CA-1 receives resources from CA-3. Before the experiment starts the system is isolated and maintains an equilibrium (homeorhesis). The three CA have the same age structure
The experiment is performed twice. In the first experiment CA-1 is injured at t =30. In the second experiment CA-2 is injured at t =30. While the somatic structure of both CA is the same, their age structures differ. The curves depict the maximal age of each CA at a given time.
Before injury, both CA have the same age structure. Injury depletes age (resources) and Max[age] of the injured CA declines. CA-1 age is replenished rapidly, since it gets resources from CA-2 and CA-3. CA-2 age is replenished slowly , since it drives resources only from CA-1.
The last figure depicts system age. Following CA-1 injury the system mobilizes more resources and mobilizes them faster, than following CA-2 injury. The first response is therefore healthier.
nca=3; zygote -> effect[no 1000]; go109]; restoreparams; injurystate[1, j, 30, 30, f[[1, 1,]], 10, 1]; injuryage[1, j, 30, 30, f[[1, 1,]], 10, 0]; support[1, 2]; support[ 2, 1]; support[ 1,3]; go; restoreparams; support[1, 2]; support[ 2, 1]; injurystate[2, j, 30, 30, f[[2, 1,]], 10, 1]; injuryage[2, j, 30, 30, f[[2, 1,]], 10, 0]; go ;