Hot from the press two renown molecular biologists publish their view of what cancer  actually is.
One delves into their complex universe only to discover  that most of it does not apply to  the cancer which is observed at the bedside.

The two views of cancer, clinical and molecular are two independent  thought styles .
Clinical arguments are based on macro cancer manifestations, e.g. symptoms and signs, and histopathological diagnosis.
Molecular arguments are based on micro cancer manifestation, e.g. genes and their products. Macro manifestations are ignored.

Medicine is approaching a conceptual  impasse. It lacks concepts to handle two attributes of the organism:  Complexity  and optimality.. The ominous process started   when molecular biology subdued clinical reasoning’s to  understand cancer. The two theories. clinical and molecular are neither compatible nor congruent.

http://www.what-is-cancer.com/indexFrame.html